Guided Learning: Coronary Artery Disease

Guided learning questions provide a systematic approach to learning by using a sequencing of the questions similar to how a topic would unfold in a traditional textbook. These guided learning questions assume the student is already knowledgeable of the content associated with the oxygen exchange and blood flow regulation guided learning topics. The student is encouraged to go not only to the initial link associated with each learning question, but also to use embedded hyperlinks to expand upon the physiological concepts associated with the question.

At the end of the guided learning questions, there is a link to an external website (testmoz.com) that has multiple choice and true/false questions that are associated with the topic. When the quiz results are given to the user after taking the quiz, links are provided back to specific cvphysiology.com pages to assist in learning. Users need to register (free) on the testmoz.com site to access the quiz questions for the tutorial. No personal information is available to cvphysiology.com apart from the user provided login name and analysis of user performance on the quiz questions. This feedback is used to improve cvphysiology.com content and quiz questions.

Guided Learning

1. What is the anatomy and distribution of major coronary vessels that supply blood flow to the myocardium?
2. Define ischemia and hypoxia.
3. How does a decrease in the myocardial oxygen supply/demand ratio lead to myocardial hypoxia?
4. What is a critical stenosis and its hemodynamic basis?
5. How does flow autoregulation partially compensate for coronary stenosis?
6. What is coronary vascular steal and its hemodynamic basis?
7. Define each of the following and state the underlying cause: chronic stable angina, Prinzmetal's (variant) angina, unstable angina, and myocardial infarction.
8. What is the role of endothelial dysfunction, particularly regarding nitric oxide production/bioavailability, in coronary artery disease and myocardial ischemia?
9. How does myocardial hypoxia alter electrical and mechanical function?

Link to Quiz Questions: testmoz.com/2479839

Revised 10/06/2023